Research interest is the visualization of cell-matrix interactions and dynamic cell patterning during immune cell interactions and tumor invasion. We, therefore, use 3D extracellular matrix (ECM) based cell culture models and advanced imaging procedures. Recently, the group moved into in vivo-imaging of tumor and immune cell migration by multiphoton microscopy. This complements in vitro culture technology. These approaches have provided insight into the serial dynamics of T cell scanning across antigen-presenting cells and the diversity of tumor invasion mechanisms, as well as novel escape responses in tumor cell migration. New technology allows imaging deep into tumours (video-interview). Personal prizes & awards 2016: ESMI award 2014: Price for the Advancement of Molecular Science from the City of Florence 2013: European Research Council - Consolidator Grant 2011: Vize-Chair and Chair (2013), Gordon Conference 2010: Vici Award, Netherlands' Science Foundation 2008: German Cancer Award, German Cancer Society 2005: Oscar-Gans Award, German Dermatological Society 2004: German Skin Cancer Award 2002: Award of the Foundation, 400 Years University of Würzburg 2001: Grünenthal Award "Skin and Environment" 1997: Hermal Early Career Award 1996: Dean's Honour List, McGill University, Montreal, Canada 1994: Felix-Wankel Animal Protection Award