Main scientific interest
My main interests in the past have been research projects in the field of neuropsychiatry, especially introduction of selegiline into the treatment strategies of Parkinson’s disease (PD) (1974/5), discovery with my co-workers of amantadines and memantines mechanisms of action (1989, 1991), discovery of the role of iron in PD (1985 – present), discovery of the loss of respiratory chain activity (complex I) in PD (1989), development of the concept of clinical neuroprotection (1983 – present), neurodevelopmental aspects of neuropsychiatric disorders (2001 – present), etiological aspects of neurodegenerative disorders.

I have a close relation to clinical research programs, human biochemistry/physiology, biochemical, molecular and pharmacological aspects of pathogenesis of neurodegenerative disorders including post mortem analysis and access to the BrainNet Europe II-initiative. This is reflected by my list of more than 1.000 publications