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个人简介
Dr. Phil Kym has been Executive Director of Drug Discovery Science & Technology since 2019 and Head of the AbbVie Medicinal Chemistry Leadership Team since 2018. In his career at Abbott/AbbVie, Phil has led teams that have discovered clinical candidates in the Neuroscience, Immunology, Oncology, Virology, Metabolic Disease, Cystic Fibrosis, and Pain therapeutic areas. He is an inventor of Foslevodopa/Foscarbidopa subcutaneous continuous infusion therapy for the symptomatic treatment of advanced Parkinson’s Disease. Phil received a B.A. in Chemistry from Goshen College, a Ph.D. in Organic Chemistry from the University of Illinois at Urbana-Champaign, and completed an American Cancer Society Postdoctoral Fellowship at the University of Texas at Austin before starting his career at Abbott/AbbVie in 1996. Phil has served on the ACS MEDI Long Range Planning Committee (2018-2020), the organizing committee for the 2022 National Medicinal Chemistry Symposium, and will be the Chair of the 2023 Gordon Research Conference on Natural Products and Bioactive Compounds.
• Head, AbbVie Medicinal Chemistry Leadership Team
• Head of Projects, AbbVie-Calico Leadership Team
• Specializes in medicinal chemistry and small molecule/ADC drug discovery
• Inventor of Foslevodopa/Foscarbidopa (ABBV-951) for the treatment of advanced Parkinson’s Disease
• Inventor of first-in-class PTPN2 phosphatase inhibitors ABBV-CLS-579 and ABBV-CLS-484 for the immunotherapy treatment of solid tumors
• Led teams that have produced 18 clinical development candidates across multiple therapeutic areas
• Active participant in ACS Pharma Leaders, ACS MEDI Long Range Planning Committee, National Medicinal Chemistry Organizing Committee, and Gordon Research Conference Chair, Natural Products
研究兴趣
论文共 145 篇作者统计合作学者相似作者
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Christina K. Baumgartner,Hakimeh Ebrahimi-Nik,Arvin Iracheta-Vellve,Keith M. Hamel,Kira E. Olander,Thomas G. R. Davis,Kathleen A. McGuire,Geoff T. Halvorsen, Omar I. Avila,Chirag H. Patel,Sarah Y. Kim,Ashwin V. Kammula,Audrey J. Muscato,Kyle Halliwill,Prasanthi Geda,Kelly L. Klinge,Zhaoming Xiong,Ryan Duggan,Liang Mu,Mitchell D. Yeary,James C. Patti,Tyler M. Balon,Rebecca Mathew,Carey Backus,Domenick E. Kennedy,Angeline Chen,Kenton Longenecker,Joseph T. Klahn,Cara L. Hrusch,Navasona Krishnan,Charles W. Hutchins,Jax P. Dunning,Marinka Bulic,Payal Tiwari,Kayla J. Colvin,Cun Lan Chuong,Ian C. Kohnle,Matthew G. Rees,Andrew Boghossian,Melissa Ronan,Jennifer A. Roth,Meng-Ju Wu,Juliette S. M. T. Suermondt,Nelson H. Knudsen,Collins K. Cheruiyot,Debattama R. Sen,Gabriel K. Griffin,Todd R. Golub,Nabeel El-Bardeesy, Joshua H. Decker,Yi Yang,Magali Guffroy,Stacey Fossey,Patricia Trusk,Im-Meng Sun,Yue Liu,Wei Qiu,Qi Sun,Marcia N. Paddock,Elliot P. Farney,Mark A. Matulenko,Clay Beauregard,Jennifer M. Frost,Kathleen B. Yates,Philip R. Kym,Robert T. Manguso
Chirag Patel,Meng Sun,Yue Liu,Jonathan Powell,Kyle Halliwill,Jennifer M Frost,Robert T Manguso,Kathleen B Yates,Hakimeh Ebrahimi-Nik,Christina K Baumgartner,Keith M Hamel,Kira Olander,Kathleen A McGuire,Audrey J Muscato,Kelly Klinge,Joseph Klahn, Jacqueline Aguado,Payal Tiwari,Kayla J Colvin,Marcia N Paddock,Philip R Kym, Omar Avila-Monge, Alexander Schutte
David R. Hill, Alexander D. Huters,Timothy B. Towne,Rajarathnam E. Reddy,Jace L. Fogle,Eric A. Voight,Philip R. Kym
Chemical Reviewsno. 23 (2023): 13693-13712
Journal of Medicinal Chemistryno. 23 (2023): 15883-15893
Wei Qiu,Qi Sun,Yi Yang,Chirag Patel,Meng Sun,Yue Liu,Kyle Halliwill,Sarah Kim,Rebecca Mathew,Jennifer M Frost,Jennifer A Roth,Domenick Kennedy,Robert T Manguso,Kathleen B Yates,Hakimeh Ebrahimi-Nik,Christina K Baumgartner,Arvin Iracheta-Vellve,Keith M Hamel,Kira Olander,Thomas GR Davis,Kathleen A McGuire,Geoff T Halvorsen, Omar I Avila,Ashwin V Kammula,Audrey J Muscato,Prasanthi Geda,Kelly Klinge,Zhaoming Xiong,Ryan Duggan,Liang Mu,Mitchell D Yeary,James C Patti,Tyler M Balon,Carey Backus,Angeline Chen,Kenton Longenecker,Joseph Klahn, Cara Hrusch,Navasona Krishnan,Charles W Hutchins, Jacqueline Aguado,Marinka Bulic,Payal Tiwari,Kayla J Colvin,Cun Lan Chuong,Ian C Kohnle,Matthew G Rees,Andrew Boghossian,Melissa Ronan,Meng-Ju Wu,Debattama R Sen,Gabriel K Griffin,Nabeel El-Bardeesy,Patricia Trusk, Joshua H Decker,Stacey Fossey,Marcia N Paddock,Elliot P Farney,Clay Beauregard,Philip R Kym
Journal for ImmunoTherapy of Cancerno. Suppl 2 (2023)
Hakimeh Ebrahimi-Nik,Arvin Iracheta-Vellve,Kira E. Olander,Thomas R. G. Davis,Sarah Y. Kim,Mitchell D. Yeary,James C. Patti,Tyler M. Balon, Omar Ismail Avila,Cun Lan Chuong,Meng-Ju Wu,Christina K. Baumgartner,Keith M. Hamel,Kathleen A. McGuire,Rebecca Mathew,Carey Backus,Ian C. Kohnle,Zhaoming Xiong,Elliot P. Farney,Jennifer M. Frost,Geoff T. Halvorsen,Matthew Rees,Andrew Boghossian,Melissa Ronan,Jennifer A. Roth,Todd R. Golub,Gabriel K. Griffin,Nabeel El-Bardeesy,Clay C. Beauregard,Philip R. Kym,Kathleen B. Yates,Robert T. Manguso
CANCER IMMUNOLOGY RESEARCHno. 12 (2022)
Arvin Iracheta-Vellve,Hakimeh Ebrahimi-Nik,Thomas R. Davis,Kira E. Olander,Sarah Y. Kim,Mitchell D. Yeary,James C. Patti,Ian C. Kohnle,Christina K. Baumgartner,Keith M. Hamel,Kathleen A. McGuire,Cun Lan Chuong,Zhaoming Xiong,Elliot P. Farney,Jennifer M. Frost,Matthew Rees,Andrew Boghossian,Melissa Ronan,Jennifer A. Roth,Todd R. Golub,Gabriel K. Griffin,Clay Beauregard,Philip R. Kym,Kathleen B. Yates,Robert T. Manguso
Cancer Researchno. 12_Supplement (2022): 606-606
Kathleen McGuire,Christina Baumgartner,Carey Backus,Rebecca Mathew,Kelly Klinge,Joseph Klahn,Prasanthi Geda,Kyle Halliwill, Jacqueline Aguado,Liang Mu,Ryan Duggan, Cara Hrusch,Elliot Farney,Zhaoming Xiong,Marinka Bulic,Patricia Trusk,Loren Lasko,Hakimeh Ebrahimi-Nik,Kathleen Yates,Robert Manguso, Keith Hamel,Marcia Paddock,Jennifer Frost,Philip Kym
Regular and Young Investigator Award Abstracts (2022)
Cancer Researchno. 12_Supplement (2022)
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作者统计
#Papers: 145
#Citation: 6707
H-Index: 46
G-Index: 79
Sociability: 7
Diversity: 3
Activity: 58
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