My research focuses largely on the pathogenic mechanism of the Buruli ulcer virulence factor, mycolactone - which you can and listen to me talking on the radio about here! http://usshl.cdn.tveyes.com/mediacat/temp/f72e1a611fe936a83deec58238e04049.mp4?start=49&end=663 My group studies macrophage and endothelial cell biology, investigating inflammatory signalling and post-transcriptional gene regulation including protein translocation through the Sec61 translocon and microRNA function.