Dr. Ueda conducted tumor antigen analysis (autologous-serum typing) to examine the reaction between kidney cancer patient serum and cultured cancer cells derived from the same patient, to find out whether the human body can recognize its cancer as a foreign substance. He was successful in identifying kidney cancer-specific antigens. Furthermore, he was a pioneer in identifying a human kidney cancer-specific antibody using a monoclonal antibody production method that had been newly developed. He was convinced that cancer immunotherapy targeting cancer-specific antigens is effective in cancer treatment, and hence he immersed himself in translational research (TR), from basic cancer research to clinical application, upon his return to Japan.