Dr. Guralnick approaches the question of global change using tools that span molecular based approaches to document lineage diversifications over time and space. These methods seek to field ecological approaches that document recent distribution and demography changes.

Although trained as an invertebrate biologist, his taxonomic interests are broad, and his work is often collaborative. Guralnick tends to be happiest when connecting dots between developing infrastructure to support new science and showing the power of those approaches for looking at broad scale ecogeographic patterns and their drivers.