Shovamayee Maharana - Department of Biological Sciences and Research Center for Excellence in MechanoBiology, National University of Singapore

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Cellular microenvironment is compartmentalized into biomolecular condensates of RNA binding proteins and RNA. These condensates are dynamic and are formed by a physicochemical process known as liquid-liquid phase separation. Importantly, changes in phase behavior of condensates are associated with pathology in many neurodegenerative disorders. We focus on understanding the role of RNA interactions in formation, phase transition and function of biomolecular condensates.

Research Interests

Papers共 25 篇Author StatisticsCo-AuthorSimilar Experts

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Algorithm for Semi-Automatic Detection of Insulin Granule Exocytosis in Human Pancreatic Β-Cells

Aishwarya A. Makam, Abhimanyu Dubey,Shovamayee Maharana,Nikhil R. Gandasi

Heliyon（2024）

Cited1Views0WOSBibtex

“Boundary Residues” Between the Folded RNA Recognition Motif and Disordered RGG Domains Are Critical for FUS–RNA Binding

Sangeetha Balasubramanian,Shovamayee Maharana,Anand Srivastava

The Journal of biological chemistry（2023）

Cited2Views0WOSBibtex

Interplay of the Folded Domain and Disordered Low-Complexity Domains along with RNA Sequence Mediate Efficient Binding of FUS with RNA

Sangeetha Balasubramanian,Shovamayee Maharana,Anand Srivastava

biorxiv（2022）

Cited2Views0Bibtex

Correlative All-Optical Quantification of Mass Density and Mechanics of Sub-Cellular Compartments with Fluorescence Specificity

Raimund Schluessler,Kyoohyun Kim,Martin Noetzel,Anna Taubenberger,Shada Abuhattum,Timon Beck,Paul Mueller,Shovamaye Maharana,Gheorghe Cojoc,Salvatore Girardo,Andreas Hermann,Simon Alberti,Jochen Guck

bioRxiv (2021)

Cited43Views0WOSBibtex

Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery

Sonja Kroschwald,Matthias C Munder,Shovamayee Maharana,Titus M Franzmann,Doris Richter,Martine Ruer,Anthony A Hyman,Simon Alberti

Cell Reports（2018）

Cited168Views0WOSBibtex

168

RNA Buffers the Phase Separation Behavior of Prion-Like RNA Binding Proteins

Shovamayee Maharana,Jie Wang,Dimitrios K. Papadopoulos,Doris Richter, Andrey Pozniakovsky,Ina Poser,Marc Bickle,Sandra Rizk,Jordina Guillen-Boixet,Titus M. Franzmann,Marcus Jahnel,Lara Marrone,Young-Tae Chang,Jared Sterneckert,Pavel Tomancak,Anthony A. Hyman,Simon Alberti

Scienceno. 6391 (2018): 918-921

Cited877Views0WOSSCIENCEBibtex

877

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