Steven Colan's research focuses on the assessment of myocardial diseases through echocardiography and other noninvasive modalities. His principal interests include evaluation of left ventricular systolic and diastolic function, clinical aspects of cardiomyopathies, and myocardial performance in congenital and acquired heart disease. To that end, many of his laboratory and clinical research projects revolve around the development and validation of non-invasive diagnostic methodologies and instruments and on the implementation of computer-based computational techniques to the analysis of cardiac physiology.