Dr. Frank’s expertise in MRI radiotherapy has led to the development and FDA approval of multiple novel positive-contrast implantable markers for use in MRI-guided LDR and HDR prostate brachytherapy and external beam radiation therapy. As founder of the company, C4 Imaging, Dr. Frank has developed the MRI marker technology at MD Anderson, has been granted 31 national and international patents, developed three FDA approved products, and has established MRI-Assisted Radiosurgery (MARS) at MD Anderson for the treatment of prostate cancer. He has funding from the NIH, the Prostate Cancer Foundation, the Texas Ignition Fund, Hitachi and MD Anderson, and he has also raised multiple rounds of private equity financing to advance the C4 technology.