Sudhir Chowdhry

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论文共 32 篇作者统计合作学者相似作者

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Enhancing Transcription-Replication Conflict Targets Ecdna-Positive Cancers

Jun Tang,Natasha E. Weiser, Guiping Wang,Sudhir Chowdhry,Ellis J. Curtis,Yanding Zhao,Ivy Tsz-Lo Wong,Georgi K. Marinov,Rui Li,Philip Hanoian,Edison Tse, Salvador Garcia Mojica,Ryan Hansen,Joshua Plum,Auzon Steffy,Snezana Milutinovic, S. Todd Meyer,Jens Luebeck, Yanbo Wang, Shu Zhang, Nicolas Altemose,Christina Curtis,William J. Greenleaf,Vineet Bafna,Stephen J. Benkovic, Anthony B. Pinkerton,Shailaja Kasibhatla,Christian A. Hassig,Paul S. Mischel,Howard Y. Chang

NATUREno. 8037 (2024)

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Preclinical and Clinical Pharmacodynamic Characterization of BBI-355, a Novel, Orally Bioavailable, and Selective CHK1 Inhibitor Being Evaluated in the First-in-human Phase 1/2 POTENTIATE Clinical Trial of Patients with Cancer Harboring Oncogene Amplifications

Debbie Liao,Ryan Hansen,Sudhir Chowdhry,Evan Holmes,Julie Wiese,Auzon Steffy,AnneMarie Pferdekamper,Edison Tse,Salvador Garcia, Rebecca Reynolds, Sara Weymer,Klaus Wagner, Chris Hassig,Shailaja Kasibhatla

Cancer Researchno. 6_Supplement (2024): 3631-3631

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Oral CHK1 Inhibitor BBI-355 Allows Flexibility of Dose and Schedule with Demonstration of Monotherapy and Combinational Antitumor Activity in Extrachromosomal DNA (ecdna) Driven Preclinical Models

Ryan J. Hansen,Auzon Steffy,Joshua Plum, Ardalan Ardeshiri,Edison Tse,Salvador Garcia, Ben Norman, Jafar Moininazeri,AnneMarie Pferdekamper,Evan Holmes,Debbie Liao, Rachelle Elsdon, Joshua Lange,Anthony Pinkerton, Julius Apuy,Sudhir Chowdhry,Christian Hassig,Shailaja Kasibhatla

Cancer Researchno. 6_Supplement (2024): 613-613

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Rampant Transcription Replication Conflict Creates Therapeutic Vulnerability in Extrachromosomal DNA Containing Cancers

crossref（2024）

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A Novel, Potent and Selective Ribonucleotide Reductase (RNR) Inhibitor, BBI-825, Blocks Extrachromosomal DNA (ecdna) Amplification-Mediated Resistance to KRASG12C Inhibitor in Colorectal Cancer (CRC)

Sudhir Chowdhry,Ryan Hansen, Jacques Mauger,AnneMarie Pferdekamper,Edison Tse, Ben Norman, Jafar Moininazeri,Salvador Garcia,Yen Truong,Debbie Liao, Joshua Lange,Evan Holmes,Anthony Celeste, Dave Solis,Auzon Steffy,Joshua Plum,Julie Wiese, Julius Apuy, Ardalan Ardeshiri,Snezana Milutinovic, Deepti Wilkinson,Anthony Pinkerton,Christian Hassig,Shailaja Kasibhatla

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

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Abstract 1626: Tumors Driven by Oncogene Amplified Extrachromosomal DNA (ecdna) Demonstrate Enhanced Sensitivity to Cell Cycle Checkpoint Kinase 1 (CHK1) Inhibition

Sudhir Chowdhry,Snezana Milutinovic,Edison Tse,Salvador Garcia,Dean Perusse, Melissa Ritland, Juyeon Ko, Deepti Wilkinson,Kristen Turner,Auzon Steffy,Joshua Plum, Ben Norman, AnnMarie Pferdekamper, Todd Meyer,Debbie Liao, Rachelle Elsdon, Joshua Lange,Anthony Pinkerton,Ryan Hansen,Christian Hassig,Shailaja Kasibhatla

Cancer Researchno. 7_Supplement (2023): 1626-1626

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Abstract B082: A Novel, Potent and Selective Ribonucleotide Reductase (RNR) Inhibitor, BBI-825, Blocks Extrachromosomal DNA (ecdna) Amplification-Mediated Resistance to KRASG12C Inhibitor in Colorectal Cancer (CRC)

Sudhir Chowdhry,Ryan Hansen, Jacques Mauger,AnneMarie Pferdekamper,Edison Tse, Ben Norman, Jafar Moininazeri,Salvador Garcia,Yen Truong,Debbie Liao, Joshua Lange,Evan Holmes,Anthony Celeste, Dave Solis,Auzon Steffy,Joshua Plum,Julie Wiese,Julius Apuy, Ardalan Ardeshiri,Snezana Milutinovic, Deepti Wilkinson,Anthony Pinkerton,Christian Hassig,Shailaja Kasibhatla

Molecular Cancer Therapeuticsno. 12_Supplement (2023)

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Tumors Driven by Oncogene Amplified Extrachromosomal DNA (ecdna) Demonstrate Enhanced Sensitivity to Cell Cycle Checkpoint Kinase 1 (CHK1) Inhibition

Sudhir Chowdhry,Snezana Milutinovic,Edison Tse,Salvador Garcia,Dean Perusse,Melissa Ritland,Juyeon Ko, Deepti Wilkinson,Kristen Turner,Auzon Steffy,Joshua Plum, Ben Norman, AnnMarie Pferdekamper,Todd Meyer,Debbie Liao, Rachelle Elsdon, Joshua Lange,Anthony Pinkerton,Ryan Hansen,Christian Hassig,Shailaja Kasibhatla

CANCER RESEARCHno. 7 (2023)

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Replication Stress and the Inability to Repair Damaged DNA, the Potential “achilles' Heel” of Ecdna+ Tumor Cells

Sudhir Chowdhry,Salvador Garcia,Nam-Phuong Nguyen,Anthony Celeste,Edison Tse,Snezana Milutinovic, Deepti Wilkinson,Christian Hassig,Shailaja Kasibhatla

CANCER RESEARCH（2022）

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论文共 32 篇作者统计合作学者相似作者