Tillie-Louise Hackett

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Research Interests:
Molecular Determinants of COPD – National Institutes for Health (2013 – 2016)
Molecular Determinants of small airway obstruction in COPD – Canadian Institutes for Health Research (2013 – 2019)
Angiotensin signaling in small airway obstruction in COPD – The Canadian Lung Association (2013 – 2015)
Defective airway epithelial differentiation in Asthma – Canadian Institutes for Health Research (2013 – 2015)
The Human Lung Cell Repository – Providence Heath Care Research Institute (2013 – 2019)

Research Interests

Papers共 236 篇Author StatisticsCo-AuthorSimilar Experts

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Computational Fluid Dynamics of Small Airway Disease in Chronic Obstructive Pulmonary Disease

Yousry K Mohamady, Vincent Geudens,Charlotte De Fays, Marta Zapata, Omar Hagrass, Lucia Aversa,Marie Vermant,Xin Jin,Lynn Willems, Iwein Gyselinck, Charlotte Hooft,Astrid Vermaut,Hanne Beeckmans, Pieterjan Kerckhof, Gitte Aerts, Celine Aelbrecht, Janne Verhaegen,Andrew Higham,Walter Coudyzer, Emanuela E Cortesi,Arno Vanstapel,John E McDonough,Marianne S Carlon,Rozenn Quarck, Matthieu N Boone,Lieven Dupont,Stephanie Everaerts, Dirk E Van Raemdonck,Laurens J Ceulemans,Tillie-Louise Hackett,Robin Vos, Yasser Abuouf,Joseph Jacob, Wim A Wuyts, James C Hogg,Marcel Filoche,Ghislaine Gayan-Ramirez,Wim Janssens,Bart M Vanaudenaerde

EBioMedicine (2025): 105670-105670

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Cellular and Molecular Features of Asthma Mucus Plugs Provide Clues about Their Formation and Persistence

Maude A Liegeois,Aileen Hsieh, May Al-Fouadi,Annabelle R Charbit,Chen Xi Yang,Tillie-Louise Hackett, John V Fahy

The Journal of clinical investigationno. 6 (2025)

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Interleukin-1α Downregulates Transforming Growth Factor-β1 or Β2-Induced Remodeling Gene Expression in Healthy Lung Fibroblasts

K. Usman,K. Nwozor,C. Yang,M. Fouadi, A. Kovtunenko,P. Nair,A. J. Halayko,T. Hackett

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2024)

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Platelet Activating Factor Receptor and Intercellular Adhesion Molecule–1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis

Affan Mahmood Shahzad,Wenying Lu,Surajit Dey,Prem Bhattarai,Archana Vijay Gaikwad,Jade Jaffar,Glen Westall,Darren Sutherland,Gurpreet Kaur Singhera,Tillie-Louise Hackett,Mathew Suji Eapen,Sukhwinder Singh Sohal

Journal of Clinical Medicine（2024）

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Volumetric Assessment of Small Airway Mucus Plugs and Lumen Narrowing in Fatal and Non-Fatal Asthma Using Microct

A. Hsieh, S. Coombes,D. M. Vasilescu,T. Hackett

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2024)

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TGFβ1, SMAD and Β-Catenin in Pulmonary Arteries of Smokers, Patients with Small Airway Disease and COPD: Potential Drivers of EndMT

Prem Bhattarai,Wenying Lu,Ashutosh Hardikar,Archana Vijay Gaikwad,Surajit Dey,Affan Mahmood Shahzad,Stephen Myers,Andrew Williams,Darren Sutherland,Gurpreet Kaur Singhera,Tillie-Louise Hackett,Mathew S. Eapen,Sukhwinder Singh Sohal

CLINICAL SCIENCEno. 17 (2024): 1055-1070

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Mechanical Properties of Asthmatic Airway Smooth Muscle

Leslie Y. M. Chin,Ynuk Bosse,Chris Pascoe,Tillie L. Hackett,Chun Y. Seow,Peter D. Pare

Airway Smooth Muscle（2024）

Cited86Views0WOSBibtex

S156 IPF Associated DNA Methylation and Gene Expression Changes in Lung Fibroblasts: Airway and Parenchymal Distinction and XY Chromosome Profiling

A Valand,P Rajasekar,AL Lagan,J Patel, B Barksby,RA Burgoyne,JL MacIsaac,DTS Lin,ST May, M Castellanos-Uribe,MS Kobor,TL Hackett,AJ Halayko, AJ Knox,A Fisher,L Borthwick, R Clifford

‘Foundation’s Edge’ (2) – Role of genetics in IPF (2024)

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Patients with Idiopathic Pulmonary Fibrosis Have Fatty Lungs Impacting Respiratory Physiology

Wenying Lu,Affan Mahmood Shahzad,Josie Larby, Maddison Waters, Melinda Wilson,Jade Jaffar,Glen Westall,Darren Sutherland,Greg Haug,Tillie L Hackett,Sukhwinder Singh Sohal

Pulmonologyno. 1 (2024): 2424637-2424637

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Associate Professor

Papers共 236 篇Author StatisticsCo-AuthorSimilar Experts