Vilja Pietiainen - Department of Virology;Haartman Institute;University of Helsinki;Haartman Institute, University of Helsinki

基本信息

Career Trajectory

Bio

Dr. Vilja Pietiainen’s research at the Institute for Molecular Medicine Finland-FIMM focuses on cancer precision medicine of solid tumors. The patient -derived cancer cells are isolated from tissues after the surgery, grown ex-vivo, and characterized with different omics technologies, including genomics, phenomics, and drug profiling. Dr. Pietiainen develops 3D platform for patient -derived cells (PDCs) and microscopic imaging –based solutions with her collaborators for phenotyping and drug profiling of PDCs. This approach enables the better understanding of the cellular heterogeneity in cancer, and drug sensitivity and resistance in particular patient. In 2017, she initiated of the new HiLIFE core unit, FIMM High Content Imaging and Analysis (FIMM-HCA) within the HELMI platform.

Research Interests

Papers共 52 篇Author StatisticsCo-AuthorSimilar Experts

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Functional Screening Identifies Kinesin Spindle Protein Inhibitor Filanesib As a Potential Treatment Option for Hepatoblastoma

Ruth Nousiainen,Katja Eloranta,Jani Saarela,Antti Hassinen, Tamara J. Luck,Stefano Cairo, Emilie Indersie, Swapnil Potdar, Michaela J. Feodoroff,Jouko Lohi,Lassi Paavolainen,David B. Wilson,Vilja Pietiäinen,Markku Heikinheimo,Marjut Pihlajoki

npj Precision Oncologyno. 1 (2025): 1-18

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Exploiting NRF2-ARE Pathway Activation in Papillary Renal Cell Carcinoma

Silvia Angori,Harini Lakshminarayanan,Amir Banaei-Esfahani, Katharina Muhlbauer,Hella Anna Bolck, Olli Kallioniemi,Vilja Pietiainen,Peter Schraml,Holger Moch

INTERNATIONAL JOURNAL OF CANCERno. 7 (2025): 1457-1469

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Genome Sequencing Reveals CCDC88A Variants in Malformations of Cortical Development and Immune Dysfunction

Johanna Lehtonen, Anna H Hakonen,Antti Hassinen, Sanne Iversen Lurås, Meri Kaustio,Virpi Glumoff, Francisca Hinrichsen, Weiwei Li, Anna-Maija Sulonen, Sanna Wickman, Henrikki Almusa, Minttu Polso,Maarit Palomäki, Sirpa Kivirikko,Kristiina Avela,Kaarina Heiskanen,Vilja Pietiäinen,Kristiina Aittomäki, Janna Saarela

Human molecular genetics (2025)

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Drug Sensitivity Profiling of 3D Tumor Tissue Cultures in the Pediatric Precision Oncology Program INFORM

ONCOLOGY RESEARCH AND TREATMENT（2024）

Cited14Views0WOSNATUREBibtex

Abstract B016: Unravelling Personalized Drug Vulnerabilities in Pediatric Solid Tumors—functional Precision Medicine Approach

Sara Kuusela, Enni Martikainen,Katja Eloranta, Wenyu Wang,Romika Kumari,Swapnil Potdar,Giovanna Dashi,Jouko Lohi,Aino Mutka,Olli Tynninen,Jukka Kanerva,Virve Pentikainen,Minna Koskenvuo,Vilja M. Pietiainen

CANCER RESEARCHno. 17 (2024)

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Morphological Single-Cell Analysis of Peripheral Blood Mononuclear Cells from 390 Healthy Blood Donors with Blood Cell Painting

Caroline Högel-Starck, Veera A. Timonen,Gantugs Atarsaikhan,Isabel Mogollon,Minttu Polso,Antti Hassinen,Jarno Honkanen, Julius Soini,Tanja Ruokoranta, Toveann Ahlnäs, Julianna Juvila,Juho J. Miettinen,Rodosthenis S. Rodosthenous,Mikko Arvas, FinnGen,Caroline A. Heckman,Jukka Partanen,Mark Daly,Aarno Palotie,Lassi Paavolainen,Vilja Pietiäinen,Esa Pitkänen

biorxiv（2024）

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Enhancing T-cell Recruitment in Renal Cell Carcinoma with Cytokine-Armed Adenoviruses

Michaela Feodoroff,Firas Hamdan,Gabriella Antignani,Sara Feola,Manlio Fusciello,Salvatore Russo,Jacopo Chiaro,Katja Valimaki,Teijo Pellinen,Rui M. Branca,Janne Lehtio,Federica D'alessio, Paolo Bottega, Virpi Stigzelius, Janita Sandberg,Jonna Clancy,Jukka Partanen, Minna Malmstedt,Antti Rannikko,Vilja Pietiaeinen,Mikaela Gronholm,Vincenzo Cerullo

ONCOIMMUNOLOGYno. 1 (2024)

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Drug Repurposing Platform for Deciphering the Druggable SARS-CoV-2 Interactome

Mariia S. Bogacheva,Suvi Kuivanen,Swapnil Potdar,Antti Hassinen,Sini Huuskonen,Ina Pohner, Tamara J. Luck,Laura Turunen,Michaela Feodoroff,Leonora Szirovicza,Kirsi Savijoki,Jani Saarela,Paivi Tammela,Lassi Paavolainen,Antti Poso,Markku Varjosalo,Olli Kallioniemi,Vilja Pietiainen,Olli Vapalahti

Antiviral Researchpp.105813-105813, (2024)

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Achieving High-Resolution Single-Cell Segmentation in Convoluted Cancer Spheroids Via Bayesian Optimization and Deep-Learning

Isabel Mogollon,Michaela Feodoroff, Pedro Neto, Alba Montedeoca,Vilja Pietiänen,Lassi Paavolainen

crossref（2024）

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Distinct Molecular Profiles and Shared Drug Vulnerabilities in Pancreatic Metastases of Renal Cell Carcinoma

Matilda Roos-Mattila,Pauliina Kallio, Tamara J. Luck,Minttu Polso,Romika Kumari,Piia Mikkonen,Katja Valimaki, Minna Malmstedt,Pekka Ellonen,Teijo Pellinen,Caroline A. Heckman,Harri Mustonen,Pauli A. Puolakkainen,Kari Alitalo,Olli Kallioniemi,Tuomas Mirtti,Antti S. Rannikko,Vilja M. Pietiainen,Hanna E. Seppanen

COMMUNICATIONS BIOLOGY（2024）

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