William Tapper

基本信息

Career Trajectory

Bio

Current research Long term follow-up of the POSH cohort to determine disease risks for distant, locoregional and new primary disease in young-onset breast cancer patients with known BRCA1/2 mutation status Genome-wide association study of outcome after aneurysmal subarachnoid haemorrhage Developing a polygenic risk score for pancreatic cancer Utilising multiomic data to understand therapy resistance in paediatric rhabdomyosarcomas Utilising patient omic information to identify target mechanisms of resistance in sarcomas Genomics of food allergy and food allergen sensitisation

Research Interests

Papers共 193 篇Author StatisticsCo-AuthorSimilar Experts

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Utility of Polygenic Risk Scores (prss) in Predicting Pancreatic Cancer: A Systematic Review and Meta-Analysis of Common-Variant and Mixed Scores with Insights into Rare Variant Analysis

Georgios Ioannis Verras, Zaed Z Hamady,Andrew Collins,William Tapper

Cancersno. 2 (2025)

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The JAK2 46/1 Haplotype Influences PD-L1 Expression

Gonzalo Carreño-Tarragona,María Tiana,Raquel Rouco,Alejandra Leivas,Jesús Victorino,Roberto García-Vicente,Andrew J. Chase, Andrea Maidana,William J. Tapper,Rosa Ayala,Nicholas C. P. Cross, Joaquín Martínez-López,Miguel Manzanares

Blood (2025)

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Lessons Learned from a Candidate Gene Study Investigating Aromatase Inhibitor Treatment Outcome in Breast Cancer

Reiner Hoppe,Stefan Winter,Wing-Yee Lo,Kyriaki Michailidou,Manjeet K Bolla,Renske Keeman,Qin Wang,Joe Dennis,Michael Lush,Krishna R Kalari,Matthew P Goetz,Liewei Wang,Junmei Cairns,Richard Weinshilboum,Lois Shepherd,Bingshu E Chen,Lothar Häberle,Matthias Ruebner,Matthias W Beckmann,Wei He,Nicole L Larson,Sebastian M Armasu,Werner Schroth,Balram Chowbay,Chiea Chuen Khor,Mustapha Abubakar,Antonis C Antoniou,Thomas Brüning,Jose E Castelao,Jenny Chang-Claude,Nbcs Collaborators,Thilo Dörk,Diana M Eccles,Jonine D Figueroa,Manuela Gago-Dominguez,José A García-Sáenz,Melanie Gündert,Carolin C Hack,Ute Hamann,Sileny Han,Maartje J Hooning,Hanna Huebner,Abctb Investigators,Esther M John, Yon-Dschun Ko,Vessela N Kristensen,Sabine Linn,Sara Margolin,Dimitrios Mavroudis,Heli Nevanlinna,Patrick Neven,Nadia Obi,Tjoung-Won Park-Simon,Katri Pylkäs,Muhammad U Rashid,Atocha Romero,Emmanouil Saloustros,Elinor J Sawyer,William J Tapper,Ian Tomlinson,Camilla Wendt,Robert Winqvist,Alison M Dunning,Jacques Simard,Per Hall,Paul D P Pharoah,Matthias Schwab,Fergus J Couch,Kamila Czene,Peter A Fasching,Douglas F Easton,Marjanka K Schmidt,James N Ingle,Hiltrud Brauch

NPJ breast cancerno. 1 (2025): 18-18

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Interactions Between Genetic and Epidemiological Factors Influencing Mammographic Density

Austin Hammermeister Suger,Hongjie Chen, Cameron B Haas, Shaoqi Fan,Christopher G Scott,Manjeet K Bolla,Joe Dennis,Alison M Dunning,Kyriaki Michailidou,Qin Wang,Peter A Fasching, Lothar Haeberle,Jennifer Stone,Manuela Gago-Dominguez, Jose E Castelao,Rachel A Murphy, Kristan Aronson,Fergus J Couch,Siddhartha Yadav,Roger L Milne,John L Hopper,Aaron Norman,A Heather Eliassen,William J Tapper, Diana M Eccles,D Gareth Evans, Susan Astley,Per Hall,Kamila Czene,Paul D P Pharoah,Antonis C Antoniou,Montserrat García-Closas, Amy Berrington,Douglas F Easton,Gretchen L Gierach,Rulla M Tamimi,Celine M Vachon,Sara Lindström, Tabitha A Harrison

American journal of epidemiology (2025)

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Sphingosine-1-phosphate Signalling in Aneurysmal Subarachnoid Haemorrhage: Basic Science to Clinical Translation

Ben Gaastra,John Zhang,Will Tapper,Diederik Bulters,Ian Galea

Translational Stroke Research（2024）

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Dissecting the Relationship Between Mosaic Loss of Chromosome Y and Sex Hormones

Ahmed Dawoud,William Tapper,Nick Cross

EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 446-446

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Spatially-resolved Tumour Infiltrating Immune Cells and Prognosis in Breast Cancer

Aaron J. Bernstein,Renske Keeman,Amber Hurson,Fiona M. Blows,Manjeet K. Bolla, Jodi L. Miller,Roger Milne,Hugo Horlings,Alexandra J. van den Broek,Clara Bodelon,James Hodge,Alpa Patel,Lauren R. Teras,Federico Canzian,Rudolf Kaaks, Hermann Brenner, Ben Schoettker,Sabine Behrens,Jenny Chang-Claude,Tabea Maurer,Nadia Obi,Fergus Couch,H. Raza Ali,Carlos Caldas,Irene Andrulis,Gord Glendon,Anna Marie Mulligan,Wilma Mesker,Agnes Jager, Annette Heemskerk-Gerritsen,Peter Devilee,Scott M. Lawrence,Jolanta Lissowska,Karun Mutreja,Thomas Ahearn,Stephen Chanock,Maire A. Duggan,Diana Eccles,J. Louise Jones,Will Tapper,Antoinette Hollestelle,Maartje Hooning,John Martens,Carolien H.M. van Deurzen,Angela Cox,Simon S. Cross,Mikael Hartman,Jingmei Li,Thomas C. Putti,Ute Hamann,Ania Jakubowska, Nicki Camp,Melissa H. Cessna,Amy Berrington de Gonzalez,Katarzyna Bialkowska,Jacek Gronwald, Jan Lubi_ski,Siddhartha Yadav,Pietro Lio,Doug F. Easton,Mustapha Abubakar,Montse Garcia-Closas,Paul D.P. Pharoah,Marjanka K. Schmidt

medrxiv（2024）

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Legends to Supplementary Figures S1 to S6 from Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy

Sofia Khan,Rainer Fagerholm,Sajjad Rafiq,William Tapper,Kristiina Aittomäki,Jianjun Liu,Carl Blomqvist,Diana Eccles,Heli Nevanlinna

openalex（2023）

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A Likelihood Ratio Approach for Utilizing Case-Control Data in the Clinical Classification of Rare Sequence Variants: Application to BRCA1 and BRCA2

Maria Zanti,Denise G. O'Mahony,Michael T. Parsons,Hongyan Li,Joe Dennis, Kristiina Aittomakkiki,Irene L. Andrulis,Hoda Anton-Culver,Kristan J. Aronson,Annelie Augustinsson,Heiko Becher,Stig E. Bojesen,Manjeet K. Bolla,Hermann Brenner,Melissa A. Brown,Saundra S. Buys,Federico Canzian,Sandrine M. Caputo,Jose E. Castelao,Jenny Chang-Claude,Kamila Czene,Mary B. Daly,Arcangela De Nicolo,Peter Devilee,Thilo Dork,Alison M. Dunning,Miriam Dwek,Diana M. Eccles,Christoph Engel,D. Gareth Evans,Peter A. Fasching,Manuela Gago-Dominguez,Montserrat Garcia-Closas,Jose A. Garcia-Saenz,Aleksandra Gentry-Maharaj,Willemina R. R. Geurts-Giele,Graham G. Giles,Gord Glendon,Mark S. Goldberg,Encarna B. Gomez Garcia,Melanie Guendert,Pascal Guenel,Eric Hahnen,Christopher A. Haiman,Per Hall,Ute Hamann,Elaine F. Harkness,Frans B. L. Hogervorst,Antoinette Hollestelle,Reiner Hoppe,John L. Hopper,Claude Houdayer,Richard S. Houlston,Anthony Howell,Abctb Investigators,Milena Jakimovska,Anna Jakubowska,Helena Jernstrom,Esther M. John,Rudolf Kaaks,Cari M. Kitahara,Stella Koutros,Peter Kraft,Vessela N. Kristensen,James Lacey,Diether Lambrechts,Melanie Leone,Annika Lindblom,Michael Lush,Arto Mannermaa,Mehdi Manoochehri,Siranoush Manoukian,Sara Margolin,Maria Elena Martinez,Usha Menon,Roger L. Milne,Alvaro N. Monteiro,Rachel A. Murphy,Susan L. Neuhausen,Heli Nevanlinna,William G. Newman,Kenneth Offit,Sue K. Park,Paul James,Paolo Peterlongo,Julian Peto,Dijana Plaseska-Karanfilska,Kevin Punie,Paolo Radice,Muhammad U. Rashid,Gad Rennert,Atocha Romero,Efraim H. Rosenberg,Emmanouil Saloustros,Dale P. Sandler,Marjanka K. Schmidt,Rita K. Schmutzler,Xiao-Ou Shu,Jacques Simard,Melissa C. Southey,Jennifer Stone,Dominique Stoppa-Lyonnet,Rulla M. Tamimi,William J. Tapper,Jack A. Taylor,Soo Hwang Teo,Lauren R. Teras,Mary Beth Terry,Mads Thomassen,Melissa A. Troester,Celine M. Vachon,Ana Vega,Maaike P. G. Vreeswijk,Qin Wang,Barbara Wappenschmidt,Clarice R. Weinberg,Alicja Wolk,Wei Zheng,Bingjian Feng,Fergus J. Couch,Amanda B. Spurdle,Douglas F. Easton,David E. Goldgar,Kyriaki Michailidou

HUMAN MUTATION（2023）

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Pharmacological EZH2 Inhibition Combined with Retinoic Acid Treatment Promotes Differentiation and Apoptosis in Rhabdomyosarcoma Cells

Eleanor O’Brien,Carmen Tse,Ian Tracy,Ian Reddin,Joanna Selfe,Jane Gibson,William Tapper,Reuben J. Pengelly,Jinhui Gao,Ewa Aladowicz,Gemma Petts,Khin Thway,Sergey Popov,Anna Kelsey,Timothy J. Underwood,Janet Shipley,Zoë S. Walters

Clinical Epigeneticsno. 1 (2023)

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Associate Professor

Papers共 193 篇Author StatisticsCo-AuthorSimilar Experts