I am an internationally respected clinical-translational investigator with a focus on genitourinary malignancies and early drug development. I have held leadership positions in National Clinical Trials Network; served as a permanent member of the oncology drug advisory committee for the FDA, and serve as the Medical Oncology Chair on the NCI Genitourinary Steering. I have overseen large basic, population and clinical NCI research programs (> 30 faculty) and have had extramural funding for the past 25 years. I am an active clinician, enjoy teaching and continue to do research in drug and biomarker development in prostate and bladder cancer and have been instrumental in defining the use of many novel therapies and biomarkers in patients with prostate and bladder cancer for all stages of this disease. I currently have over 250 publications.