His main area of clinical research is investigating innovative methods of assessment of microcirculation in critically ill patients. The coordination and data management of large European multicentre studies (SOAP, EPIC II, ICON, and IC-GLOSSARI studies) are included in his prominent research activities over the last few years.

Dr. Sakr is a member of the European Society of Intensive Care (ESICM) since 2003 and has actively contributed to the activities of the various sections of the society, especially the SIS section. He coordinated a major study, endorsed by the ESICM from 2001 to 2010 (the SOAP study) and is the PI of a recent trial initiated by the trials’ group of this society. He is currently Chairman of the Systemic Inflammation and Sepsis section of the ESICM.