She is a world-renown leader, researcher, virologist and clinician in the field of HIV pathogenesis, prevention and treatment of maternal-fetal and pediatric HIV-1, and is an active member of the Pediatric AIDS Clinical Trial Group. She is currently the Chair of the NIH Network IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials) PMTCT Committee (Prevention of Mother-to-Child Transmission of HIV). An invited member on the U.S. Public Health Service Task Force on the Use of Zidovudine to Reduce Perinatal Transmission of Human Immunodeficiency Virus, Dr. Bryson was influential in the development of CDC and Public Health guidelines for the diagnosis and treatment of HIV-infected pregnant women and has been involved in the planning and execution of national cooperative studies of maternal-fetal HIV transmission.