Understanding and Modulating Cyclin-Dependent Kinase Inhibitor Specificity: Molecular Modeling and Biochemical Evaluation of Pyrazolopyrimidinones As CDK2/cyclin A and CDK4/cyclin D1 Inhibitors
Journal of Computer-Aided Molecular Design（2005）
关键词
ATP-competitive,cancer,cyclin-dependent kinase (CDK),docking,homology,selectivity
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