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Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (Lfa-1): Structure-Activity Relationships Leading to the Identification of 6-((5S,9r)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1 ,3,7-Triazaspiro[4.4]nonan-7-yl)nicotinic Acid (Bms-688521)

Scott H. Watterson,Zili Xiao,Dharmpal S. Dodd,David R. Tortolani,Wayne Vaccaro,Dominique Potin,Michele Launay,Dawn K. Stetsko,Stacey Skala,Patric M. Davis,Deborah Lee,Xiaoxia Yang,Kim W. McIntyre,Praveen Balimane,Karishma Patel,Zheng Yang, Punk Marathe,Pathanjali Kadiyala,Andrew J. Tebben,Steven Sheriff,ChiehYing Y. Chang,Theresa Ziemba,Huiping Zhang,Bang-Chi Chen,Albert J. DelMonte,Nelly Aranibar,Murray McKinnon,Joel C. Barrish,Suzanne J. Suchard,T. G. Murali Dhar

Journal of Medicinal Chemistry（2010）

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