Structure-based Library Design and the Discovery of a Potent and Selective Mast Cell Β-Tryptase Inhibitor As an Oral Therapeutic Agent
Bioorganic & Medicinal Chemistry Letters（2011）
关键词
Serine protease,Asthma,COPD,Tryptase,Inhibitor,Molecular modeling,Structure-based drug design,X-ray,Benzylamine
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