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Design, Synthesis, and Evaluation of Imidazo[4,5-C]pyridin-4-one Derivatives with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-Γ

Agustin Casimiro-Garcia,Ronald J. Heemstra,Christopher F. Bigge,Jing Chen,Fred A. Ciske,Jo Ann Davis,Teresa Ellis,Nadia Esmaeil,Declan Flynn,Seungil Han,Mehran Jalaie,Jeffrey F. Ohren,Noel A. Powell

Bioorganic & Medicinal Chemistry Letters（2012）

Cited 26|Views26
Key words
Angiotensin,Peroxisome proliferator-activated receptor,PPAR gamma,Hypertension,Metabolic syndrome
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