Effects of Particle Size, Food, and Capsule Shell Composition on the Oral Bioavailability of Dabrafenib, a BRAF Inhibitor, in Patients with BRAF Mutation-Positive Tumors.
Journal of Pharmaceutical Sciences（2013）
Key words
dabrafenib,food effects,particle size,bioavailability,HPMC,gelatin,capsules,supersaturation,dissolution,clinical pharmacokinetics
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