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A Phase I, Open-Label, Single-Arm, Dose-Escalation Study of E7107, a Precursor Messenger Ribonucleic Acid (Pre-Mrna) Splicesome Inhibitor Administered Intravenously on Days 1 and 8 Every 21 Days to Patients with Solid Tumors

D. S. Hong,R. Kurzrock,A. Naing,J. J. Wheler,G. S. Falchook,J. S. Schiffman, N. Faulkner,M. J. Pilat, J. O’Brien,P. LoRusso

Investigational New Drugs（2014）

引用 168|浏览8
关键词
Advanced solid tumors,E7107,Pharmacodynamic,Pharmacokinetic,Phase I
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