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Progressive Increase in Mtdna 3243A>G Heteroplasmy Causes Abrupt Transcriptional Reprogramming

Martin Picard,Jiangwen Zhang,Saege Hancock,Olga Derbeneva,Ryan Golhar,Pawel Golik,Sean O'Hearn,Shawn Levy,Prasanth Potluri,Maria Lvova,Antonio Davila,Chun Shi Lin,Juan Carlos Perin,Eric F. Rappaport,Hakon Hakonarson,Ian A. Trounce,Vincent Procaccio,Douglas C. Wallace

Proceedings of the National Academy of Sciences（2014）

Cited 312|Views24
Key words
RNA-Seq,mitochondrial disease,mtDNA variant,epigenetic,electron microscopy
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