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Augmented Binary Substitution: Single-pass CDR Germ-Lining and Stabilization of Therapeutic Antibodies

Sue Townsend,Brian J. Fennell,James R. Apgar,Matthew Lambert,Barry McDonnell, Joanne Grant,Jason Wade,Edward Franklin,Niall Foy,Deirdre Ni Shuilleabhain,Conor Fields,Alfredo Darmanin-Sheehan,Amy King,Janet E. Paulsen,Timothy P. Hickling,Lioudmila Tchistiakova,Orla Cunningham,William J. J. Finlay

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA（2015）

Cited 41|Views45
Key words
antibody,paratope,plasticity,humanization,immunogenicity
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