PARP Activity in Peripheral Blood Lymphocytes As a Predictive Biomarker for PARP Inhibition in Tumor Tissues - A Population Pharmacokinetic/pharmacodynamic Analysis of Rucaparib.
Clinical Pharmacology in Drug Development（2014）
Key words
rucaparib,pharmacokinetics (PK)/pharmacodynamics (PD),poly (ADP-ribose) polymerase ( PARP),mixed-effects modeling,biomarker
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