A Chemical and Computational Approach to Comprehensive Glycation Characterization on Antibodies.
mAbs（2015）
Key words
glycation,targeted mass spectrometry,boronate affinity chromatography,structural modeling,angstrom,angstroms,BA,boronate affinity chromatography,CDR3,complementary-determining region 3,CEX,cation exchange chromatography,CID,collision induced dissociation,CV,coefficient of variation,Da,daltons,EIC,extracted ion chromatogram,HC-CDR3,heavy chain complementary determining region 3,HPLC,high performance liquid chromatography,LC-MS2,liquid chromatography coupled with tandem mass spectrometry,mAb,monoclonal antibody,MS1,a mass to charge ratio survey scan,MS2,tandem mass spectrometry - selected ions from MS1 are fragmented and fragment ion mass measured,UPLC,ultrahigh performance liquid chromatography
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