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    • Nano-mole Scale Sequential Signal Assignment by (1)H-Detected Protein Solid-State NMR.

    Songlin Wang,Sudhakar Parthasarathy,Yiling Xiao,Yusuke Nishiyama,Fei Long,Isamu Matsuda,Yuki Endo,Takahiro Nemoto,Kazuo Yamauchi,Tetsuo Asakura,Mitsuhiro Takeda,Tsutomu Terauchi,Masatsune Kainosho,Yoshitaka Ishii

    Chemical Communications（2015）SCI 2区

    Univ Illinois | JEOL RESONANCE Inc | King Abdullah Univ Sci & Technol | Tokyo Univ Agr & Technol | Nagoya Univ | SAIL Technol Inc

    Cited 38|Views28
    Abstract
    We present a 3D 1H-detected solid-state NMR (SSNMR) approach for main-chain signal assignments of 10–100 nmol of fully protonated proteins.
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    【要点】：本文提出了一种3D (1)H-检测固态核磁共振技术，实现了10-100纳摩尔量级全质子化蛋白质主链信号的精确分配，提高了信号分配的速度和准确性。
    

    【方法】：通过使用3D (1)H-检测固态NMR技术，对蛋白质主链的化学位移、偶合常数和远程连接进行分析。
    

    【实验】：实验使用未知具体名称的数据集，通过固态NMR技术成功完成了对蛋白质样本的信号分配，并验证了方法的有效性。
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