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Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain.

Jillian R. Brown,Wenyong Tong,Chrissa A. Dwyer,Bryan E. Thacker,Charles A. Glass,Kristina Hamill,Kelley W. Moremen,Stephane Sarrazin,Philip L. S. M. Gordts,Gentry Patrick,Lara E. Dozier,Yitzhak Tor,Jonathan Cooper,Patricia I. Dickson,Jeffrey D. Esko

Molecular Genetics and Metabolism（2018）

Cited 10|Views11

Key words

mucopolysaccharidoses,enzyme-replacement therapy,guanidinoglycosides,neuropathology,intranasal delivery

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