Adverse Outcome Pathways: Opportunities, Limitations and Open Questions
Archives of Toxicology（2017）
关键词
Regulatory toxicology,Systems biology,Multi-scale integration,Computational toxicology,Interspecies extrapolation,Metabolism,Pathway unidirectionality,Liver fibrosis,Paracetamol,CCl4,Vinyl acetate,Tumor promotion,Binning of events,Multiple hit events,Proof of non-toxicity,Prioritization of compounds
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