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The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in T(8;21) AMLs

Amit Mandoli,Abhishek A. Singh,Koen H. M. Prange,Esther Tijchon, Marjolein Oerlemans,Rene Dirks,Menno Ter Huurne,Albertus T. J. Wierenga,Eva M. Janssen-Megens,Kim Berentsen,Nilofar Sharifi,Bowon Kim,Filomena Matarese,Luan N. Nguyen,Nina C. Hubner,Nagesha A. Rao,Emile van den Akker,Lucia Altucci,Edo Vellenga,Hendrik G. Stunnenberg,Joost H. A. Martens

Cell Reports（2016）

Cited 56|Views55
Key words
AML1-ETO,acute myeloid leukemia,epigenome,RUNX1,iPSC,apoptosis
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