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BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder.

Lawrence R. Marcin,Jayakumar Warrier,Srinivasan Thangathirupathy,Jianliang Shi,George N. Karageorge,Bradley C. Pearce,Alicia Ng,Hyunsoo Park,James Kempson,Jianqing Li,Huiping Zhang,Arvind Mathur, Aliphedi B. Reddy,G. Nagaraju,Gopikishan Tonukunuru, Grandhi V. R. K. M. Gupta, Manjunatha Kamble,Raju Mannoori,Srinivas Cheruku,Srinivas Jogi,Jyoti Gulia, Tanmaya Bastia,Charulatha Sanmathi, Jayant Aher,Rajareddy Kallem,Bettadapura N. Srikumar,Kumar Kuchibhotla Viaya,Pattipati S. Naidu,Mahesh Paschapur,Narasimharaju Kalidindi,Reeba Vikramadithyan,Manjunath Ramarao,Rex Denton,Thaddeus Molski,Eric Shields,Murali Subramanian,Xiaoliang Zhuo,Michelle Nophsker,Jean Simmermacher,Michael Sinz,Charlie Albright,Linda J. Bristow,Imadul Islam,Joanne J. Bronson,Richard E. Olson,Dalton King,Lorin A. Thompson,John E. Macor

ACS Medicinal Chemistry Letters（2018）

Cited 17|Views66
Key words
BMS-986163,BMS-986169,GluN2B,negative allosteric modulator,ketamine,depression,preclinical candidate
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