Development of a Target Cell-Biologics-effector Cell (TBE) Complex-Based Cell Killing Model to Characterize Target Cell Depletion by T Cell Redirecting Bispecific Agents
mAbs(2018)
关键词
mechanism-based pharmacokinetic-pharmacodynamic modeling,bispecific antibodies (bsAbs),Target cell-Biologics-Effector cell (TBE) complex,cell killing model,T cell redirecting,immune oncology,tumor immunotherapy
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