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Discovery and Optimization of a Novel Series of Pyrazolyltetrahydropyran N-type Calcium Channel (cav 2.2) Blockers for the Treatment of Pain

Mark J. Wall,Nalin L. Subasinghe,Michael P. Winters,Mary Lou Lubin,Michael F. A. Finley,Ning Qin,Michael R. Brandt,Michael P. Neeper,Craig R. Schneider,Raymond W. Colburn,Christopher M. Flores,Zhihua Sui

Bioorganic & Medicinal Chemistry Letters（2018）

引用 6|浏览35
关键词
Pain,N-type calcium channel,Cav 2.2,Pyrazoles,CFA model,CCI model
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