A Class of Highly Selective Inhibitors Bind to an Active State of PI3Kγ

Gangadhara,Göran Dahl,Thomas Bohnacker,Rebecca Rae,Jenny Gunnarsson,Stefan Blaho,Linda Öster,Helena Lindmark,Kostas Karabelas,Nils Pemberton,Christian Tyrchan,Mickael Mogemark,Matthias P. Wymann,Roger L. Williams,Matthew W. D. Perry,Tineke Papavoine,Jens Petersen

Nature Chemical Biology（2019）

引用 43|浏览58

关键词

Kinases,Mechanism of action,Small molecules,X-ray crystallography,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry

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