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Discovery and Optimization of Quinolinone Derivatives As Potent, Selective and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (midh1) Inhibitors.

Jian Lin,Wei Lu,Justin A. Caravella,Ann Marie Campbell, R. Bruce Diebold,Anna Ericsson, Edward Fritzen,Gary R. Gustafson,David R. Lancia, Tatiana Shelekhin,Zhongguo Wang,Jennifer Castro,Andrea Clarke,Deepali Gotur,Helen R. Josephine,Marie Katz, Hien Diep,Mark Kershaw,Lili Yao,Goss Kauffman,Stephen E. Hubbs,George P. Luke,Angela V. Toms,Liann Wang,Kenneth W. Bair,Kenneth J. Barr,Christopher Dinsmore,Duncan Walker,Susan Ashwell

Journal of Medicinal Chemistry（2019）

Cited 34|Views17
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