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Utility of in Vitro Bioactivity As a Lower Bound Estimate of in Vivo Adverse Effect Levels and in Risk-Based Prioritization

Katie Paul Friedman,Matthew Gagne,Lit-Hsin Loo,Panagiotis Karamertzanis,Tatiana Netzeva,Tomasz Sobanski,Jill A. Franzosa,Ann M. Richard,Ryan R. Lougee,Andrea Gissi,Jia-Ying Joey Lee,Michelle Angrish,Jean Lou Dorne, Stiven Foster,Kathleen Raffaele,Tina Bahadori,Maureen R. Gwinn,Jason Lambert,Maurice Whelan,Mike Rasenberg,Tara Barton-Maclaren,Russell S. Thomas

TOXICOLOGICAL SCIENCES（2020）

Cited 179|Views23
Key words
high-throughput screening,high-throughput toxicokinetics,threshold of toxicological concern (TTC),point-of-departure (POD),new approach methodologies
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