Characterization of Bispecific and Mispaired IgGs by Native Charge-Variant Mass Spectrometry

Wilson Phung,Guanghui Han,Stephanie G. Polderdijk,Michael Dillon,Whitney Shatz,Peter Liu,Bingchuan Wei,Pawankumar Suresh,David Fischer,Christoph Spiess,Aaron Bailey,Paul J. Carter,Jennie R. Lill,Wendy Sandoval

International Journal of Mass Spectrometry（2019）

Cited 12|Views45

Key words

Bispecific antibody,Cognate pairs,Single cell,Charge variant mass spectrometry,Ion exchange chromatography,Weak cation exchange,Native mass spectrometry,Molecular model,Mispaired antibody

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