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Design and Synthesis of Conformationally Constrained RORγt Inverse Agonists

Ayumu Sato,Yoshiyuki Fukase,Mitsunori Kono,Atsuko Ochida,Tsuneo Oda,Yusuke Sasaki,Naoki Ishii,Yoshihide Tomata,Shoji Fukumoto,Yumi N. Imai,Keiko Uga,Akira Shibata,Masashi Yamasaki,Hideyuki Nakagawa,Mikio Shirasaki,Robert Skene,Isaac Hoffman,Bi-Ching Sang,Gyorgy Snell,Junya Shirai,Satoshi Yamamoto

ChemMedChem（2019）

引用 8|浏览45
关键词
conformationally constrained scaffolds,interleukin 17,inverse agonists,ROR gamma,u-shaped
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