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An Engineered Human Fc Domain That Behaves Like a Ph-Toggle Switch for Ultra-Long Circulation Persistence

Chang-Han Lee,Tae Hyun Kang,Ophélie Godon,Makiko Watanabe,George Delidakis,Caitlin M. Gillis,Delphine Sterlin,David Hardy,Michel Cogné,Lynn E. Macdonald,Andrew J. Murphy,Naxin Tu,Jiwon Lee,Jonathan R. McDaniel,Emily Makowski,Peter M. Tessier,Aaron S. Meyer,Pierre Bruhns,George Georgiou

Nature Communications（2019）

Cited 56|Views55

Key words

Genetic engineering,Protein design,Science,Humanities and Social Sciences,multidisciplinary

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