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Impact of Minor Structural Modifications on Properties of a Series of Mtor Inhibitors

Gilles Ouvry,Laurence Clary,Loic Tomas,Michele Aurelly,Laetitia Bonnary, Emilie Borde,Claire Bouix-Peter,Laurent Chantalat, Claire Defoin-Platel,Sophie Deret,Mathieu Forissier,Craig S. Harris,Tatiana Isabet,Laurent Lamy,Anne-Pascale Luzy,Jonathan Pascau,Catherine Soulet, Alessandro Taddei,Nathalie Taquet,Etienne Thoreau, Emeric Varvier,Emmanuel Vial,Laurent F. Hennequin

ACS Medicinal Chemistry Letters（2019）

Cited 7|Views24

Key words

mTOR,kinase,selectivity,metabolism,topical application

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