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Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity

Sun K. Ho,Zhenghai Xu,Archana Thakur,Melvin Fox,Siu Sze Tan,Enrico DiGiammarino,Li Zhou,Mien Sho,Belinda Cairns,Vivian Zhao,Mengli Xiong,Josue Samayoa,Charles M. Forsyth,David B. Powers,Debra T. Chao,Diane Hollenbaugh,Hamsell M. Alvarez,Yoshiko Akamatsu

openalex（2023）

引用 29|浏览22
关键词
Tumor Immunity,Tumor Antigen,Therapeutic Antibodies
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