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Design and Synthesis of Novel Proline Based Factor XIa Selective Inhibitors As Leads for Potential New Anticoagulants.

Zahid Hussain,Andrew J. Cooke,Santhosh Neelamkavil,Lindsay Brown,Emma Carswell,Wayne M. Geissler,Zhuyan Guo,Brian Hawes,Terri M. Kelly,Yasuko Kiyoi,KehDih Lai,Charles Lesburg,Eleanor Pow,Yi Zang,Harold B. Wood,Scott D. Edmondson,Weiguo Liu

Bioorganic & Medicinal Chemistry Letters（2020）

Cited 7|Views49
Key words
Factor XIa (FXIa) inhibitor,Thrombin (FIIa),Proline analogs,Anticoagulants,Thrombosis
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