Translational Strategy Using Multiple Nuclear Imaging Biomarkers to Evaluate Target Engagement and Early Therapeutic Efficacy of SAR439859, a Novel Selective Estrogen Receptor Degrader.

Laurent Besret,Sébastien d’Heilly, Cathy Aubert,Guillaume Bluet,Florence Gruss-Leleu, Françoise Le-Gall,Anne Caron, Laurent Andrieu,Sylvie Vincent,Maysoun Shomali,Monsif Bouaboula, Carole Voland,Jeffrey Ming,Sébastien Roy,Srinivas Rao,Chantal Carrez,Erwan Jouannot

EJNMMI Research（2020）

引用 10|浏览14

关键词

SAR439859,Estrogen-positive breast cancer,SERD,Target engagement,Combination therapy,Palbociclib,Positron emission tomography,[18F]-FDG,[18F]-FES,[18F]-FLT

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