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In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying Mrna Regulation

Sean Mc Cafferty,Joyca De Temmerman,Tasuku Kitada,Jacob R. Becraft,Ron Weiss,Darrell J. Irvine,Mathias Devreese,Siegrid De Baere,Francis Combes,Niek N. Sanders

MOLECULAR THERAPY（2021）

Cited 16|Views38
Key words
self-amplifying mRNA,synthetic biology,translational control,destabilizing domain,L7Ae,RNA-binding protein,trimethoprim,erythropoietin
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