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Mechanistic Insights into the Synergistic Activation Ofthe RXR–PXR Heterodimer by Endocrinedisruptor Mixtures

V. Delfosse,T. Huet,D. Harrus,M. Granell,M. Bourguet, C. Gardia-Parege,B. Chiavarina,M. Grimaldi,S. Le Mevel,P. Blanc, D. Huang,J. Gruszczyk,B. Demeneix,S. Cianferani,J-B. Fini,P. Balaguer,W. Bourguet

Acta Crystallographica Section A Foundations and Advances（2021）

引用 45|浏览43
关键词
Cocktail effect,low dose,endocrine disruptor,nuclear receptors,synergy,binding cooperativity
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