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Design and Optimisation of Dendrimer-Conjugated Bcl-2/xL Inhibitor, AZD0466, with Improved Therapeutic Index for Cancer Therapy

Claire M. Patterson,Srividya B. Balachander,Iain Grant,Petar Pop-Damkov,Brian Kelly,William McCoull,Jeremy Parker,Michael Giannis,Kathryn J. Hill,Francis D. Gibbons,Edward J. Hennessy,Paul Kemmitt,Alexander R. Harmer,Sonya Gales,Stuart Purbrick,Sean Redmond,Matthew Skinner,Lorraine Graham,J. Paul Secrist,Alwin G. Schuller,Shenghua Wen,Ammar Adam,Corinne Reimer,Justin Cidado,Martin Wild,Eric Gangl,Stephen E. Fawell,Jamal Saeh,Barry R. Davies,David J. Owen,Marianne B. Ashford

Communications Biology（2021）

Cited 67|Views49
Key words
Drug delivery,Drug development,Haematological cancer,Targeted therapies,Life Sciences,general
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