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Development and Scale-Up of a Direct Asymmetric Reductive Amination with Ammonia

Alison Campbell Brewer,J. Craig Ruble, H. George Vandeveer,Scott A. Frank,C. Richard Nevill

Organic Process Research & Development（2021）

Cited 22|Views10
Key words
direct asymmetric reductive amination,chiral primary amine,cGMP,iPr-DUPHOS,dtbm-Segphos,ruthenium
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