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误诊为病毒性脑炎后遗症的异染性脑白质营养不良1例报告

Beijing Medical Journal(2018)

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Abstract
患儿 女,2岁5个月,因“运动、智力进行性倒退13个月”于2016年6月27日来我院就诊.患儿入院前1年因当地诊断手足口病后1周左右发现走路不稳并呈进行性加重,伴有四肢肌张力增高,于多家医院就诊,患病15d全脊髓MRI、头颅MRI平扫+弥散成像、脑脊液常规、生化均未见明显异常.肌电图示多发性周围神经源性损害电生理改变.所查运动神经及感觉神经传导速度减慢.体感诱发电位(somatosensory evoked potential,SEP)示左、右N9~N20和N 13~N20峰间潜伏期均延长,左右P40和T12潜伏期均延长.
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