COX-2抑制剂在消化道肿瘤防治中的研究进展
MEDICAL RECAPITULATE(2004)
Abstract
环氧合酶(cyclooxygenase,COX)是前列腺素(PGs)合成过程中的一个重要限速酶,目前发现其主要存在两种亚型:COX-1和COX-2.近年来研究发现COX-2与消化系肿瘤关系密切,其不仅在消化道肿瘤中有较高表达,并可能参与肿瘤的增殖、转移及分化.
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