急性脑梗死患者血清超敏C-反应蛋白和纤维蛋白原检测的临床意义
Shandong Medical Journal(2018)
Abstract
目的 探究血清超敏C-反应蛋白(hs-CRP)、和纤维蛋白原(FIB)水平检测急性脑梗死患者临床诊断及治疗的应用价值.方法 选取急性脑梗死患者98例(观察组),按照神经功能缺损程度评分分为重度脑梗死28例、中度脑梗死38例、轻度脑梗死32例,参照CT/MRI扫描结果分为大面积脑梗死36例、小面积脑梗死30例、腔隙性脑梗死32例;另选择同期性别、年龄构成匹配体检健康者49例(对照组).检测两组血清hs-CRP、FIB水平及观察组不同梗死程度、不同梗死面积患者的血清hs-CRP、FIB水平.结果 观察组血清hs-CRP、FIB水平均高于对照组(P均<0.05).轻度、中度、重度脑梗死患者血清hs-CRP、FIB水平依次增高,不同梗死程度患者血清hs-CRP、FIB水平比较有统计学意义(P均<0.05).大面积、小面积、腔隙性脑梗死患者血清hs-CRP、FIB水平依次增高,不同脑梗死面积患者血清hs-CRP、FIB水平比较有统计学意义(P均<0.05).结论 血清hs-CRP、FIB水平检测对急性脑梗死患者病情严重程度及病灶面积大小评估有重要价值.
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